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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAT
All Species:
13.33
Human Site:
S254
Identified Species:
32.59
UniProt:
P04040
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04040
NP_001743.1
527
59756
S254
V
E
D
A
A
R
L
S
Q
E
D
P
D
Y
G
Chimpanzee
Pan troglodytes
XP_001147928
527
59674
S254
V
E
D
A
A
R
L
S
Q
E
D
P
D
Y
G
Rhesus Macaque
Macaca mulatta
XP_001115625
527
59924
S254
V
E
D
A
A
R
L
S
Q
E
D
P
D
Y
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P24270
527
59747
A254
V
G
E
A
G
R
L
A
Q
E
D
P
D
Y
G
Rat
Rattus norvegicus
P04762
527
59739
A254
V
E
E
A
G
R
L
A
Q
E
D
P
D
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507740
575
65276
S302
V
E
E
A
G
R
L
S
R
E
D
P
D
Y
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080544
528
60240
A254
V
D
E
A
N
R
L
A
A
S
D
P
D
Y
G
Zebra Danio
Brachydanio rerio
Q9PT92
526
59636
A254
V
E
E
A
D
R
L
A
A
T
D
P
D
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17336
506
57131
A252
V
K
T
A
D
Q
L
A
S
T
D
P
D
Y
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27487
500
57448
A250
V
E
K
A
G
Q
L
A
S
S
D
P
D
Y
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.5
N.A.
N.A.
89.5
88.9
N.A.
77.3
N.A.
80.8
76.8
N.A.
63.9
N.A.
60.5
N.A.
Protein Similarity:
100
99.4
98.4
N.A.
N.A.
95.2
94.8
N.A.
84.1
N.A.
88.8
86.9
N.A.
77.2
N.A.
75.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
80
N.A.
80
N.A.
60
60
N.A.
46.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
93.3
N.A.
93.3
N.A.
80
73.3
N.A.
66.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
30
0
0
60
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
30
0
20
0
0
0
0
0
100
0
100
0
0
% D
% Glu:
0
70
50
0
0
0
0
0
0
60
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
40
0
0
0
0
0
0
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
0
0
20
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
80
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
40
20
20
0
0
0
0
30
% S
% Thr:
0
0
10
0
0
0
0
0
0
20
0
0
0
0
0
% T
% Val:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _